Research Assistant
![tenun Samed Güner, M.Sc.](https://cbr.cs.tum.de/wp-content/uploads/sites/18/2024/03/tenun.png)
Tenuun Bayaraa, Dr.
Research Assistant
Phone: +49 (0) 9421 187-338
Fax: +49 (0) 9421 187-310
Mail: tenuun.bayaraa@tum.de
TUM Campus Straubing
Schulgasse 16
D-94315 Straubing
Schulgasse 16, Room A1.08
Vita
Curriculum
- Aug 2023 – Current: Postdoctoral Researcher at the Chair of Biogenic Resources, Technical University of Munich, Straubing, Germany
- May 2023 – Aug 2023: Postdoctoral Researcher at the School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia
- Jan 2019 – May 2023: PhD in Biochemistry at the School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia
- PhD thesis title: Structure, function, and inhibition of Fe-S cluster-dependent dehydratases from the ilvD/EDD family
- Oct 2022 – May 2023: Senior Research Assistant at the Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Australia
- Jul 2014 – Nov 2018: Bachelor of Biotechnology Class I Honours at the School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia
- Honours thesis title: Inhibitors of KARI as anti-tuberculosis drug leads
Research
My research focuses on establishing one-pot multi-enzyme cascades to produce valuable chemical products from renewable feedstocks such as various sugars. The main focus is on the characterisation and optimisation of the various enzymes within these cell-free cascades. Improving the properties of the bottleneck enzymes for increased activity, substrate promiscuity, solvent tolerance and thermostability via enzyme engineering is vital to the success of these cell-free enzymatic cascades. Furthermore, improving the overall efficiency and yield of the multi-enzymatic systems is essential to become industrially applicable for sustainable production
Publications
- Bayaraa, T. Lonhienne, S. Sutiono, O. Melse, T. B. Brück, E. Marcellin, P. V. Bernhardt, M. Boden, J. R. Harmer, V. Sieber, L. W. Guddat, G. Schenk, Structural and Functional Insight into the Mechanism of the Fe-S Cluster-Dependent Dehydratase from Paralcaligenes ureilyticus, Chemistry – A European Journal, Nov 2022
- Bayaraa, J. Gaete, S. Sutiono, J. L. Kurz, T. Lonhienne, J. R. Harmer, P. V. Bernhardt, V. Sieber, L. W. Guddat, G. Schenk, Dihydroxy-Acid Dehydratases from Pathogenic Bacteria: Emerging Drug Targets to Combat Antibiotic resistance, Chemistry – A European Journal, May 2022
- Bayaraa, J. L. Kurz, K. M. Patel, W. M. Hussein, J. K. Bilyj, N.P. West, G. Schenk, R. P. McGeary, L. W. Guddat, Discovery, Synthesis and Evaluation of a Ketol-Acid Reductoisomerase Inhibitor, Chemistry – A European Journal, Feb 2020