Research associate

Dr. Josef Sperl
Dr. Josef Sperl

Research associate

Phone: +49 (0) 9421 187-322
Fax: +49 (0) 9421 187-310

TUM Campus Straubing
Schulgasse 16
Germany, 94315 Straubing

Schulgasse 16, Room: 1.A07


Curriculum vitae:

  • Research associate at the Chair of Chemistry of Biogenic Resources, Technical University of Munich (since 2014)
  • Doctorate at the Institute of Biophysics and Physical Biochemistry, University of Regensburg, Prof. R. Sterner (2009-2013)
  • Diploma thesis at the Institute for Biophysics and Physical Biochemistry of the University of Regensburg (2009)
  • Studies of Chemistry at the University of Regensburg (2004-2009)


  • Biocatalysis
  • Multienzymatic Cascades
  • Renewable raw materials
  • Provision of basic chemicals for the chemical industry


  • Sperl JM and Sieber V (2018) Multienzyme Cascade Reactions—Status and Recent Advances. ACS Catal.8, pp 2385–2396
  • Sperl JM, Carsten JM, Guterl J-K, Lommes P, Sieber V (2016) Reaction Design for the Compartmented Combination of Heterogeneous and Enzyme Catalysis. ACS Catalysis, 6(10):6329–6334.
  • Carstensen L, Sperl JM, Bocola M, List F, Schmid FX, Sterner R. (2012). Conservation of the folding mechanism between designed primordial (βα)8-barrel proteins and their modern descendant. J Am Chem Soc. 1;134(30):12786-91.
  • Sperl JM, Rohweder B, Rajendran C, Sterner R. (2013). Establishing catalytic activity on an artificial (βα)8-barrel protein designed from identical half-barrels. FEBS Lett. 2;587(17):2798-805.
  • Reisinger B, Sperl J, Holinski A, Schmid V, Rajendran C, Carstensen L, Schlee S, Blanquart S, Merkl R, Sterner R. (2014). Evidence for the existence of elaborate enzyme complexes in the Paleoarchean era. J Am Chem Soc. 8;136(1):122-9.


Chair of Chemistry of Biogenic Resources

Schulgasse 16
D-94315 Straubing


Prof. Dr. Volker Sieber

Phone: +49 (0) 9421 187-300
Phone: +49 (0) 8161 71 35 91

Team Assistant

Elisabeth Aichner

Phone: +49 (0) 9421 187-301