Group Leader and Research Fellow
Amelie Skopp, Dr.
Research Assistant
Phone: +49 (0) 9421 187-345
Fax: +49 (0) 9421 187-310
Mail: amelie.skopp@tum.de
TUM Campus Straubing
Schulgasse 16
D-94315 Straubing
Schulgasse 16, Room
Vita
Curriculum
- Since 4/2022: Research Associate at the Chair of Chemistry of Biogenic Resources
- 04/2019-03/2022: Research Associate at Aeglea Therapeutics, Inc. in Austin, TX, USA
- Field of research: development of therapeutic human enzymes for the treatment of genetic diseases
- 05/2017-12/2018: PhD at the University of Texas at Dallas, Dallas, TX, USA. Principal Investigator Prof. Dr. Duane Winkler
- Dissertation topic: “Copper Trafficking to the Metalloenzyme SOD1”.
- 08/2014-05/2017: Master studies at the University of Texas at Dallas, Dallas, TX, USA.
- Field of research: “Structural studies of the histone chaperone FACT”.
- 08/2011-06/2014: Bachelor studies in Biochemistry and Cell Biology at Jacobs University Bremen.
- Topic of bachelor thesis: “Applications of biotechnological methods to the study of endocytosis – a theoretical and practical approach”.
Research
- Bio-based coatings and paints
- Biohybrid catalytic materials
- Sensing and indicator materials
- Solid-state gas-phase catalysis
- Biotransformation
- Bioremediation
Publications
Skopp A, Boyd SD, Ullrich MS, Liu L, Winkler DD. Activation of copper-zinc superoxide dismutase (Sod1) terminates the interaction between its copper chaperone (Ccs) and the cytosolic metal-binding domain of copper importer Ctr1. Biometals. 2019 Aug;32(4):695-705. doi: 10.1007/s10534-019-00206-3. epub 2019 Jul 10. PMID: 31292775.
Boyd SD, Ullrich MS, Skopp A, Winkler DD. Copper sources for Sod1 activation. Antioxidants (Basel). 2020 Jun 7;9(6):500. doi: 10.3390/antiox9060500. PMID: 32517371
Boyd SD, Calvo JS, Liu L, Ullrich MS, Skopp A, Meloni G, Winkler DD. The yeast copper chaperone for copper-zinc superoxide dismutase (CCS1) is a multifunctional chaperone that promotes all stages of SOD1 maturation. J Biol Chem. 2019 Feb 8;294(6):1956-1966. doi: 10.1074/jbc.RA118.005283. epub 2018 Dec 10. PMID: 30530491.
Winans S, Larue RC, Abraham CM, Shkriabai N, Skopp A, Winkler D, Kvaratskhelia M, Beemon KL. The FACT complex promotes DNA integration of avian leukosis virus. J Virol. 2017 Mar 13;91(7):e00082-17. doi: 10.1128/JVI.00082-17. print 2017 Apr 1. PMID: 28122976.